کلیدواژهها
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Ferroptosis, Hematological malignancies, Nanomedicine, Ferroptosis inducers, Novel strategies
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چکیده
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The latest fndings in iron metabolism and the newly uncovered process of ferroptosis have paved the way for new
potential strategies in anti-leukemia treatments. In the current project, we reviewed and summarized the current
role of nanomedicine in the treatment and diagnosis of leukemia through a comparison made between traditional
approaches applied in the treatment and diagnosis of leukemia via the existing investigations about the ferroptosis
molecular mechanisms involved in various anti-tumor treatments. The application of nanotechnology and other novel
technologies may provide a new direction in ferroptosis-driven leukemia therapies. The article explores the potential
of targeting ferroptosis, a new form of regulated cell death, as a new therapeutic strategy for leukemia. It discusses
the mechanisms of ferroptosis and its role in leukemia and how nanotechnology can enhance the delivery and ef‑
cacy of ferroptosis-inducing agents. The article not only highlights the promise of ferroptosis-targeted therapies
and nanotechnology in revolutionizing leukemia treatment, but also calls for further research to overcome challenges
and fully realize the clinical potential of this innovative approach. Finally, it discusses the challenges and opportunities
in clinical applications of ferroptosis
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