مشخصات پژوهش

صفحه نخست /A Search for Eurasian Sheep ...
عنوان
A Search for Eurasian Sheep Relationships: Genomic Assessment of the Autochthonous Sheep Breeds in Russia and the Persian Plateau
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
local breeds; single nucleotide polymorphisms; migrations; Silk Road
چکیده
Genomic assessment of local sheep breeds is relevant to the reconstruction of postdomestication migrations and to filling in gaps in the developmental history and contemporary phylogeographic-differentiation patterns in Eurasia. In this study, we aimed to reveal possible genetic relationships between local sheep breeds in Russia and the Persian Highlands (Iran) based on high-density SNP genotypes. All samples (n = 395) from 11 Iranian and 10 Russian sheep breeds were genotyped by using the Ovine Infinium HD BeadChip (Illumina, San Diego, CA, USA). Principal Component Analysis, maximum-likelihood assessment, and Neighbor-Net graph analysis demonstrated a clear differentiation between Russian sheep breeds of European ancestry from the Iranian local cluster and Russian breeds of Asian origin. Admixture analysis revealed a shared ancestral background, which was detected in several Iranian-local and Russian-local fat-tailed coarse-wool sheep breeds. Our findings contribute to a better understanding of the pattern of historic admixture, which is present in the genomes of many Eurasian sheep breeds.
پژوهشگران تاتیانا دنیسکووا (نفر اول)، علی اسماعیلی زاده کشکوئیه (نفر دوم)، آرسن دوستف (نفر سوم)، اولگا کوشکینا (نفر چهارم)، محمد علی فره وشی (نفر پنجم)، مرتضی مختاری (نفر ششم به بعد)، مژده موسی نژاد خبیصی (نفر ششم به بعد)، فنگ-هوا ال وی (نفر ششم به بعد)، ناتالیا زینویوا (نفر ششم به بعد)