مشخصات پژوهش

صفحه نخست /Design, synthesis and ...
عنوان
Design, synthesis and biological evaluation of new substituted benzofuran-based derivatives via C−H bond activation
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
Carbon-carbon coupling, benzofuran, acetylcholinesterase, Alzheimer’s disease
چکیده
A series of biologically active disubstituted benzofuran derivatives (3a– d) have been designed and synthesized via C-H bond activation reaction. The chemical structures of all final compounds were confirmed by spectroscopic methods. In vitro anti acetylcholinesterase (AChE) activities of these novel compounds were evaluated and showed low to moderate results. Among them, compounds 3d moderately inhibited AChE activities with 68.12 % values
پژوهشگران بهجت پورامیری (نفر اول)، محبوبه زاهدی فر (نفر دوم)، عدیله آیتی (نفر سوم)، فرح پورامیری (نفر چهارم)، مهدیه احمدی (نفر پنجم)