ccomplishing the objectives of optimal and sustainable management in the agricultural sector is increasingly getting
complicated, which includes increasing the sustainable productivity of water and energy resources, ensuring food security,
decreasing contaminations from fertilizers and chemical pesticides, and environmental destruction. The present research
deals with designing the relationships between the water-energy-food nexus approach with economic and environmental
objectives to accomplish the aforementioned objectives. Hence, a multi-objective programming model was developed to
maximize the water-energy-food nexus index and farmers’ gross margin, minimize the use of chemical fertilizers (nitrogen
and phosphate), and minimize the use of chemical pesticides (herbicides) by considering the balancing constraint to
groundwater resources. Afterward, the proposed multi-objective model was solved using the augmented e-constraint
method, and then the total of strong and efficient Pareto solutions was extracted. Then, the best solution was chosen using
the TOPSIS method and assigning a weight of equal importance to the desired objectives. The irrigation network of Jiroft
plain in Kerman province in Iran was chosen as the study area to implement such a system. The obtained results indicated
that the optimal and sustainable management in the agriculture sector can be hopeful using the proposed approach in the
current research. On the other hand, the results revealed that despite considering the economic objective in the proposed
system, the farmers’ profits can be significantly decreased. Thus, the realization of optimal and sustainable management in
the agricultural sector is not possible without the implementation of policies for increasing the economic incentive of
farmers.