This study identifies key factors affecting dust susceptibility in Gavkhouni Basin, central Iran, using three feature selection
algorithms and a perceptual neural network model. Accuracy assessment statistics were used to evaluate the prediction
capabilities of the models. The aerosol optical depth dataset validated the dust-generating area map, with the permutation
feature importance method prioritizing factors controlling dust events. Using the variables selected by the genetic algorithm
improved the coefficient of explanation by 31% compared to relief, and 19% compared to ElasticNet algorithm. The genetic
algorithm proved effective in identifying variables that significantly enhanced model accuracy in high-risk zones (precision
= 0.75, recall = 0.71, and F1 = 0.73). The study found that topographic diversity, geology, soil sand content, precipitation,
wind speed, soil salinity, soil subsidence, vegetation cover, slope, and soil moisture were key environmental factors. These
findings are very important for the formulation of specific measures for improving air quality and limiting dust-related effects
as a key factor in the sustainable management of vulnerable ecosystems.