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Abstract
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The utilization of silver nanoparticles (AgNPs) in diverse fields, including
medicine, is on the rise, leading to the development of a non-toxic
and environmentally friendly synthesis method. This study presents a
straightforward and stable one-step synthesis of AgNPs using an aqueous
extract of Amygdalus lycioides as both a reducing and stabilizing agent. The
experimental findings demonstrated that the presence of Amygdalus lycioides
extract results in the formation of AgNPs with smaller size, uniformity,
and well-dispersed nanostructures. The synthesis process is significantly
influenced by certain reaction parameters such as the molar ratio of AgNO3
,
temperature, and extract volume. Characterization of the nanostructures
was performed using XRD, UV-Vis, FT-IR, DLS, and SEM measurements.
Furthermore, the AgNPs exhibited potent antibacterial effects, leading to cell
death through increasing the membrane permeability and disrupting bacterial
wall integrity. Additionally, this research explores the fungicidal characteristics
of the colloidal solution of nanosized silver as a potential antifungal treatment
against various plant pathogens. Based on the obtained results, AgNPs exhibit
varying levels of antifungal activity against these plant pathogens. Molecular
docking calculations revealed the binding energy between Ag metal and
bacteria. These findings pave the way for effective and novel antimicrobial
therapies as alternatives to traditional antifungal and antibacterial drugs,
thereby addressing the challenges of microbial resistance and the difficulty of
eradicating infections in the near future
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