University of Jiroft | Mahboobeh Zahedifar

Research

Title	1. The condensation of (chlorocarbonyl)phenyl ketene with 1,3-Dinucleophiles.II. preparation of 2-hydroxy-3-phenyl-4H-pyrimido[2,1-b][1,3]benzothiazol-4-ones and thioxo dihydro-4,6-(1H,5H)pyrimidinones.
Type	Article
Keywords	chlorocarbonyl)phenylketene), pyrimido[2,1-b][1,3]benzothiazol)-
Researchers	Hassan Sheibani, Mahboobeh Zahedifar

Abstract

A simple one-pot and efficient method is described for the synthesis of 2-hydroxy-3-phenyl-4H-pyrimido[2,1-b][1,3]benzothiazol-4-one and thioxodihydro-4,6(1H,5H)-pyrimidinone derivatives via the reaction of (chlorocarbonyl)phenylketene with 1,3-dinucleophiles such as 2-aminobenzothiazoles and N-arylthioureas respectively. This method offers a simple and convenient route to prepare the title compounds in good to excellent yields in a short reaction time