University of Jiroft | Mahboobeh Zahedifar

Research

Title	New synthesis of 7-hydroxy-6-phenyl-3-(aryldiazenyl)pyrazolo[1,5- a]pyrimidine-2,5(1H,4H)-dione derivatives from the reaction of (chlorocarbonyl)phenyl ketene and 5-aminopyrazole-3-one derivatives
Type	Presentation
Keywords	pyrazolo[1,5-a]pyrimidine derivatives, (chlorocarbonyl)phenyl ketene, 5-aminopyrazole- 3-ones.
Researchers	Mahboobeh Zahedifar, Hassan Sheibani

Abstract

A simple one-pot and effective method is pronounced for the synthesis of 7-hydroxy-6-phenyl-3- (aryldiazenyl)pyrazolo[1,5-a]pyrimidine-2,5(1H,4H)-dione derivatives 3 via the 1,3- binucleophilic reaction of (chlorocarbonyl)phenyl ketene 2 with 5-aminopyrazole-3-ones 1. This method proposals a simple and suitable route to the synthesis of pyrazolo[1,5-a]pyrimidine derivatives 3 in good to excellent yield in a short reaction times.