Mahboobeh Zahedifar

Multicomponent reactions (MCRs) are considered as one of the best routes in organic and medicinal findings.1,2 heterocyclic compounds containing quinoline and pyrazole ring systems, such as pyrazolo[4,3-c]quinoline3 and pyrazolo[3,4-b]quinoline4 play an important role in medicinal chemistry and drug discovery.5,6 Among these compounds, pyrazolo[3,4-b]quinoline framework provides significant pharmacological activities such as antiviral,7 antimalarial,8 and anti-inflammatory.9 A great number of reports on the synthesis of pyrazolo[3,4-b]quinoline by the multicomponent reactions have been published thus-far.10