Aquaculture is one of the fastest-growing industries in the world, and its prominent role has been proven in supplying food
for the growing world population. The expected growth of aquaculture requires the development of responsible and sustainable approaches, technologies, culture systems, and practices. The integrated multitrophic aquaculture (IMTA) system
has been developed over the past decades. This system is based on the use of all food levels for simultaneous production
of some aquaculturally species in a way that contributes to environmental sustainability (biocontrol), economic stability
(product diversity and risk reduction), and social acceptance (better management operations). In IMTA, selecting suitable
culture species and considering their appropriate population size is absolutely necessary to achieve an optimal biological
and chemical process, improving the ecosystem health and sustainability of the industry. Biofoc technology (BFT) is closely
related to the IMTA system, where the IMTA potential can be used to control suspended solids in aquaculture systems with
limited water exchange. This study reviews the signifcance of IMTA systems, potential target species for cultivation, the
relationship between BFT and IMTA, total suspended solids control, the economics of IMTA farming, and the recent fndings in these felds.