University of Jiroft | seyed hamze hosseini

Research

Title	A new diterpenoid from Salvia santolinifolia boiss
Type	Article
Keywords	Quinone diterpenoids; Salvia; antibacterial activity; Lamiaceae
Researchers	Zahra Sargazifar, Marziyeh Esmaeilzadeh Kashi, Zahra Tazik, Javad Mottaghipisheh, seyed hamze hosseini, Hermann Stuppner, ابوالفضل شاكري, Javad Asili

Abstract

Phytochemical study of the Salvia santolinifolia root extract resulted in the isolation of one new quinone diterpenoid, aegyptinone E (1) as well as two known ones, aegyptinone A (2) and aegyptinone D (3). All the isolated compounds were reported for the first time from S. santolinifolia. Spectroscopic analyses including 1D and 2D NMR and HRESIMS were used to determine the chemical structures. Aegyptinone A (2) showed moderate antibacterial activity against Staphylococcus aureus, Staphylococcus epidermis, and Bacillus subtilis with MIC of 25 lg/mL.