The commuting graph of a non-commutative ring R
denoted by (R) is a graph whose vertices are non-central elements
of R and two distinct vertices x and y are adjacent if xy = yx. Let
D be a division ring, F = Z(D) and m2 = dimFD. In this paper,
we show that if F ̸= D or n > 2 and the eld F has no extension
of degree mn then (Mn(D)) is a connected graph whose diameter
is less than ve. Also we prove that the diameter of (M2(H)) is
four where H is a quaternion algebra over a eld F which has no
extension of degree 4 and Char(F) ̸= 2.