November 23, 2024
ali akbari

ali akbari

Academic rank: Associate professor
Address: kerman, Jiroft, km 8 Bandar Abbas Road, University Of Jiroft
Education: PhD. in Organic chemistry
Phone: +98 3443347061
Faculty:

Research

Title
Design of a new method for the synthesis of novel 2-aryl/alkyl-3H-indol-3-ones.
Type Article
Keywords
Organic catalysis · Heterocycles · Synthetic design · Indol-3-one
Researchers ali akbari, neda Seyedi, Muhammad Saleh Faryabi

Abstract

In this research, a mild, efficient, and general method has been developed to synthesize the new derivatives of 2-aryl/alkyl-3H-indol-3-ones in moderate to excellent yields. This method allowed the syntheses of these compounds via the three-component reaction of anhydride compound, sodium cyanide, and aniline derivatives using acetic anhydride as an organic catalyst in one-pot reactions. The advantages of this method include mild reaction conditions, simple procedures, and easy workup.