Objectives The aim of this study was to examine the antibacterial activities of benzohydrazide derivatives.
Methods: Manganese hydrogen sulfate choline chloride was applied in a simple method for synthesizing
benzohydrazide derivatives. Antibacterial activities of the derivatives were assessed against Staphylococcus
aureus, Escherichia coli, Enterococcus faecalis, Bacillus subtilis, diphtheroids, Salmonella enterica, Serratia
marcescens, Pseudomonas aeruginosa, and Klebsiella pneumoniae. The structure of the synthesized
compounds was determined employing 1H/13C NMR and Fourier-transform infrared (FT-IR) spectroscopy. The
reactions were carried out in choline chloride dissolved in water at room temperature.