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Abstract
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Phytochemical study of the Salvia santolinifolia root extract
resulted in the isolation of one new quinone diterpenoid, aegyptinone
E (1) as well as two known ones, aegyptinone A (2) and
aegyptinone D (3). All the isolated compounds were reported for
the first time from S. santolinifolia. Spectroscopic analyses including
1D and 2D NMR and HRESIMS were used to determine the
chemical structures. Aegyptinone A (2) showed moderate antibacterial
activity against Staphylococcus aureus, Staphylococcus epidermis,
and Bacillus subtilis with MIC of 25 lg/mL.
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